Effect of Acetyl-L-Carnitine on Leukemia L1210 Resistant to Mitoxantrone
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چکیده
منابع مشابه
Acetyl-L-Carnitine Monograph
Introduction Acetyl-L-carnitine (ALC) is an ester of the trimethylated amino acid, L-carnitine, and is synthesized in the human brain, liver, and kidney by the enzyme ALC-transferase. Acetyl-L-carnitine facilitates the uptake of acetyl CoA into the mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. ALC, simila...
متن کاملThe effect of acetyl l-carnitine on ultrastructure of injured motoneuron synapses in adult rat
Background and Objective: Spinal cord compression is a relatively common neurological complication in developing country. This study was designed to assess neuroprotective effect of acetyl L-carnitine. Materials and Methods: 16 adult Sprague Dawley rats weighing 250 to 300 g were divided into 4 randomized groups, namely, A-laminectomy with daily intraperitoneal injection of acetyl L-carnitine....
متن کاملEvaluation of the protective effect of L-carnitine and acetyl-L-carnitine on human spermatozoa during freezing and thawing
Materials and methods: Semen samples were collected from 20 normal healthy volunteers. Specimens were divided into 2 aliquots (A and B) and each diluted in Ham's F-10 media to a uniform concentration of 20X10/mL. Aliquots A, were further divided and into each L-carnitine or acetyl-L-carnitine were added in concentrations of 0, 10, and 30 μM separately. All aliquots were cryopreserved for 3 days...
متن کاملThe Effect of Acetyl-L-Carnitine on Learning and Spatial Memory Deficit in Diabetic Rats
Background & Aims: Diabetes mellitus is a chronic metabolic disorder that in the long-term is accompanied with deficits in learning, memory, and cognitive skills. Due to the existing evidence regarding the anti-diabetic potential of acetyl-L-carnitine (ALC), the effect of its long-term administration on learning and spatial memory deficits was investigated in diabetic rats. Methods: In this exp...
متن کاملThe Effects of L-carnitine and L-acetyl- carnitine on in vitro sperm maturation
Received: 13 November 2010 Revised: 16 May 2011 Accepted: 15 June 2011 Abstract Background: Sperm cells extracted from testes (TESE) have poor chromatin quality and motility. Various substances are used in the laboratory to increase sperm motility and improve the ART outcomes; however, there are few research which considered improving both sperm motility and chromatin quality. Objective: The ai...
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ژورنال
عنوان ژورنال: Acta Medica (Hradec Kralove, Czech Republic)
سال: 2000
ISSN: 1211-4286,1805-9694
DOI: 10.14712/18059694.2019.125